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This SOP is relevant for Procedure and calibration of disintegration test apparatus (Electrolab make), which can be employed for finding disintegration time of capsules or tablets in good quality control Section.

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Put one compressed pessary over the higher perforated disc and canopy the apparatus by using a glass plate to be certain a humid atmosphere. Repeat the Procedure with an extra two compressed pessaries.

Very last Updated on: February 2, 2024 by Naresh Bhakar Disintegration test apparatus is extensively Employed in pharmaceuticals to detect the disintegration Attributes of assorted varieties of tablets and capsules.

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At the conclusion of the closing date as specified, carry the basket from fluid and observe the tablets, all of the tablets have to disintegrate wholly.

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Disintegration is outlined as that condition through which no residue from the tablet and capsule remains on the monitor in the apparatus

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If discs are actually employed with capsules, any residue remaining over the reduce surfaces on the discs is composed only of fragments of shells.

For converting the typical basket to Specific covered version for testing challenging or soft gelatine capsules accepting to USP Chapter

Fix the exterior probe of respective jar into the beaker utilizing clip. Insert the probe in to the beaker and guarantee probe is straight rather than touching the glass beaker as well as basket.

twenty five mm underneath the surface of drinking water and at its lowest stage is read more no less than 25mm previously mentioned The underside of beaker.